Table 1.
Baseline characteristics of the study population
| Characteristic | Controls (n = 20) | Parkinson disease (n = 16) | Huntington disease (n = 15) | Prodromal Huntington disease (n = 5) |
|---|---|---|---|---|
| Demographics | ||||
| Age, years | 58±16.2 | 68±8.7 | 55±10.7 | 38±8.6 |
| Sex (women), % | 70 | 44 | 20 | 40 |
| Ethnicity (white), % | 90 | 94 | 100 | 100 |
| Hispanic ethnicity, % | 0 | 0 | 0 | 0 |
| Education (4-year college degree or higher), % | 50 | 100 | 53 | 40 |
| Currently employed or student, % | 45 | 19 | 13 | 60 |
| Currently married or in a domestic partnership, % | 85 | 100 | 53 | 0 |
| Disease characteristics | ||||
| Years since diagnosis | NA | 4.9±4.2 | 8.2±4.9 | NA |
| Unified Huntington's Disease Rating Scale– total motor score (0–124)a | 1.7±2.3 | NA | 42.7±10.9 | 3.4±4.4 |
| Unified Huntington's Disease Rating Scale– total maximal chorea score (0–28)a | 0.0±0.0 | NA | 11.9±3.0 | 1.8±3.5 |
| Movement Disorder Society– Unified Parkinson's Disease Rating Scale– total motor score (0–132)a | 1.9±2.1 | 20.7±8.3 | NA | NA |
| Timed Up and Go, s | 7.8±1.8 | 10.5±2.8 | 11.1±5.2 | 7.6±2.1 |
| 10-m Walk Test, s | 3.9±0.7 | 4.7±1.1 | 5.4±2.0 | 3.6±0.6 |
| Montreal Cognitive Assessment score (0–30)b | 28.1±1.4 | 27.3±2.2 | 19.9±3.8 | 27.0±2.5 |
| Internet and technology use | ||||
| Used Internet or email, % | 100 | 100 | 73 | 100 |
| Used Internet to look up health information, % | 90 | 100 | 53 | 80 |
| Used smartphone or tablet to access Internet, % | 95 | 94 | 53 | 100 |
| Used computer or other device to video chat, % | 100 | 88 | 40 | 60 |
All values are mean± standard deviation unless otherwise noted. NA, not applicable.
a
Higher score indicates greater disability.
b
Higher score indicates greater cognitive function, score≥26 is“normal.”