Table 3. Average survival time and risk for recurrence of disease of CRC patients with biomarker(+) or biomarker(-) lymph nodes.

		Survival time after surgery			Risk for recurrence
Biomarker	mRNA level* (copies/18S rRNA unit)	Average** (months)	Difference vs marker(-) (months)	P-value	Hazard ratio***	P-value
CEACAM5(-)	<4.2	112
CEACAM5(+)	≥4.2	44	68	<0.0001	4.67	<0.0001
KLK6 (-)	<0.0831	110
KLK6 (+)	≥0.0831	46	64	<0.0001	4.01	<0.0001
SLC35D3 (-)	<0.0059	103
SLC35D3 (+)	≥0.0059	54	49	0.002	2.48	0.002
MUC2 (-)	<0.0045	108
MUC2 (+)	≥0.0045	64	44	0.001	2.53	0.001
POSTN (-)	<11.05	107
POSTN (+)	≥11.05	76	31	0.001	2.52	0.002

* The cut-off level is the 80^th percentile of the patient population.

** Mean survival time after surgery as calculated by cumulative survival analysis according to Kaplan-Meier.

*** Risk ratio as calculated according to univariate Cox's regression analysis.