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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Hypertension. 2019 Dec 23;75(2):449–457. doi: 10.1161/HYPERTENSIONAHA.119.13822

Figure 4. The sex differences in natriuretic responses to acute volume expansion are dependent on macula densa NOS1β.

Figure 4.

The changes in GFR (A), urine flow rate (B) and sodium excretion (C) during the 0-60 minute period and 60-90 minute period after acute volume expansion in male and female NOS1flox/flox mice, as well as KO mice. n=6; *P<0.01 versus baseline; #P<0.05 versus male mice. Statistical difference was calculated by two-way ANOVA followed by Sidak multiple comparisons test.