Table 2.
Correlations Between FGF21, Leptin, Adiponectin, TNFα, and Body Composition Blood Markers at Baseline in Total Participants
| FGF21 | Leptin | Adiponectin | TNFα | |||||
|---|---|---|---|---|---|---|---|---|
| Measure | Coefficient (r) | P -value | Coefficient (r) | P -value | Coefficient (r) | P -value | Coefficient (r) | P - value |
| BMI (kg/m2) | 0.49 | 0.09 | 0.69 | 0.01 | 0.02 | 0.95 | -0.27 | 0.33 |
| fat mass (kg) | 0.41 | 0.17 | 0.87 | <0.001 | -0.13 | 0.67 | -0.42 | 0.12 |
| % fat mass | 0.38 | 0.21 | 0.85 | <0.001 | -0.37 | 0.22 | -0.56 | 0.03 |
| SAT (cm3) | 0.43 | 0.14 | 0.80 | 0.001 | -0.18 | 0.55 | -0.46 | 0.09 |
| VAT (cm3) | 0.25 | 0.40 | 0.54 | 0.06 | -0.18 | 0.56 | -0.08 | 0.79 |
| SSAT (cm3) | 0.43 | 0.14 | 0.75 | 0.003 | -0.16 | 0.60 | -0.35 | 0.20 |
| DSAT (cm3) | 0.42 | 0.16 | 0.81 | 0.001 | -0.19 | 0.53 | -0.52 | 0.05 |
| REE (kcal/day) | 0.15 | 0.63 | 0.65 | 0.02 | -0.15 | 0.62 | -0.25 | 0.37 |
| Glucose (mmol/L) | -0.15 | 0.63 | 0.04 | 0.90 | 0.12 | 0.71 | -0.01 | 0.99 |
| Insulin (µIU/L) | 0.05 | 0.88 | 0.29 | 0.34 | -0.22 | 0.48 | -0.27 | 0.34 |
| HDL (mmol/L) | -0.31 | 0.31 | -0.62 | 0.02 | 0.58 | 0.04 | 0.38 | 0.17 |
| Triglyceride (mmol/L) | -0.25 | 0.41 | 0.13 | 0.66 | -0.45 | 0.12 | 0.16 | 0.56 |
| NEFA (mmol/L) | -0.27 | 0.38 | 0.05 | 0.88 | 0.50 | 0.08 | 0.34 | 0.22 |
N = 19, Correlations were used to assess relationship between variables after adjusting for sex. Significant correlations between variables are shown in bold with corresponding coefficient (r) and P values adjusted for sex.
Abbreviations: BMI, body mass index (calculated as body weight [kg] divided by the square of height [m]); DSAT, deep subcutaneous adipose tissue; FGF21, fibroblast growth factor-21, HDL, high-density lipoprotein; NEFA, non-esterified fatty acids; REE, resting energy expenditure; SAT, subcutaneous adipose tissue; SSAT, superficial subcutaneous adipose tissue; TNFα, tumor necrosis factor-alpha; VAT, visceral adipose tissue.