Table 1.
Hormonal tests of the proband.
| Treatment | Age | TSH mIU/l | FT4 (ng/dl) | FT3 (pg/dl) | IGF1 (ng/ml) | IGFBP3 (ug/ml) | GH (ng/ml) | Cortisol (ug/dl) | ACTH (pg/ml) |
|---|---|---|---|---|---|---|---|---|---|
| No treatment | 3 days | 7.52 (0.7–15.2) | 1.02 (0.9–2.5) | – | – | – | – | – | – |
| 3 years 5 months | 4.3 (0.7–6.0) | 0.51* (1.0–1.8) | – | <25 (22–229) | 0.9 (0.9–4.3) | – | 4.2* (5–25) | – | |
| 3 years 6 months | 5.09 (0.7–6.0) | 0.62* (1.0–1.8) | – | – | – | 0.50* [1] (>10) | 6.2 [1] (5–25) | 29.9 (7.2–63) | |
| – | – | – | – | – | 0.66* [2] (>10) | 16.6 [2] (5–25) | – | ||
| – | – | – | – | – | 0.88* [3] (>10) | – | – | ||
| – | – | – | – | – | 0.85* [4] (>10) | – | – | ||
| – | – | – | – | – | 1.01* [5] (>10) | – | – | ||
| Norditropin® and Eltroxin | 3 years 9 months | <0.005 (0.7–6.0) | 1.31 (1.0–1.8) | 4.68 (2.8–4.4) | – | – | – | – | – |
| 3 years 11 months | – | 1.11 (1.0–1.8) | – | <25 (22–229) | 1.2 (0.9–4.3) | – | – | – | |
| 5 years 10 months | – | – | – | 45 (39–250) | 2.4 (1.1–5.2) | – | – | – | |
| 6 years 6 months | <0.0025 (0.6–4.8) | 1.38 (1.0–1.7) | – | 107 (47–275) | – | – | – | – | |
| 6 years 9 months | – | 1.41 (1.0–1.7) | – | – | – | – | – | – | |
| 6 years 10 months | – | 1.77 (1.0–1.7) | – | 79.6 (47–275) | – | – | – | – | |
*not in normal range
Numbers in parentheses are normal ranges.