FIG 4.

Evolutionary conservation of HrmK in cyanobacteria. Shown is a heat map depicting the percent identity for orthologs of N. punctiforme HrmK in cyanobacteria, derived from data reported by Cho et al. (26). The species organization and phylogenetic tree are based on the phylogeny reported by Shih et al. (36) but depicting the finding, as reported by Schirrmeister et al. (37), that most extant cyanobacteria are derived from a filamentous ancestor. For the phylogenetic tree, green indicates filamentous and black indicates unicellular.