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. 2020 Jan 10;86(2):291–302. doi: 10.1111/bcp.14139

Table 5.

Most frequently identified factors that contributed to the development of preventable events (N = 782)

Contributing factors identified among 782 preventable ADEsa n (%)
Communication problem Lack of communication between a healthcare provider and a patient 58 (7.4)
Lack of communication between physicians 18 (2.3)
Lack of communication between nurses 6 (0.8)
Lack of communication between physician and pharmacist 3 (0.4)
Lack of communication between physician and a nurse 3 (0.4)
Lack of communication between pharmacists 2 (0.3)
Drug delivery/labelling/packaging/storage problem Drug name, label or packaging problem 1 (0.1)
Drug storage or delivery problem 1 (0.1)
EMS problem Ambulance did not transport hypoglycaemic patient to hospital 3 (0.4)
Error Provider error in drug administration 1 (0.1)
Inadequate monitoring Delay in or inadequate clinical reassessment after medication change 122 (15.6)
Insufficient laboratory monitoring 120 (15.3)
Too aggressive medical therapy for patient's condition/age 36 (4.6)
Mental health illness/social problem‐related Non‐adherence associated with mental health illness 53 (6.8)
Patient confusion/dementia 16 (2.0)
Substance misuse 15 (1.9)
Missing information Critical information missing that could have prevented or mitigated the ADE 31 (4.0)
Non‐adherence Patient preference to not take medications 49 (6.3)
Prior ADE leading to patient non‐adherence 38 (4.9)
Patient self‐titrating medications inappropriately 30 (3.8)
No compliance aid when required 20 (2.6)
Patient non‐adherence due to financial/lack of coverage 18 (2.3)
Regimen too complex (e.g., high number of daily doses) 11 (1.4)
Patient missed doses (forgetfulness/intoxication) 10 (1.2)
Patient error in administration 7 (0.9)
Patient hearing problem 1 (0.1)
Prior ADE Missed/misdiagnosed previous ADE 3 (0.4)
Provider‐level problem Provided inadequate patient education or instructions 186 (23.8)
Provider non‐adherence with current treatment guidelines 101 (12.9)
Lack of staff education 43 (5.5)
Medication prescribed inappropriately because patient insisted 18 (2.3)
Prescribed despite lack of clear indication for the culprit drug 10 (1.2)
Systems level problem Environmental problem 4 (0.5)
Lack of quality control or independent check systems 4 (0.5)
Unable to access care Patient unable to access a prescription refill 44 (5.6)
Patient unable to access GP for appointment 15 (1.9)
Patient unable to access specialist for appointment 8 (1.0)
Patient unable to access appropriate level of care 4 (0.5)
aThere were 87 preventable adverse drug events with no identified contributing factors