Table 1.
Baseline patient demographics and laboratory values
| Patient characteristics | n | Mean (SD) | Median (range) |
|---|---|---|---|
| Age (y) | 178 | 1.72 (0.97) | 1.8 (0.02–4.7) |
| BSA (m2) | 178 | 0.52 (0.12) | 0.53 (0.2–0.82) |
| Height (cm) | 178 | 81.0 (12.8) | 82.0 (48.0–82.0) |
| Weight (kg) | 178 | 11.4 (3.66) | 11.5 (2.80–20.9) |
| SCr (mg/dL) | 178 | 0.20 (0.05) | 0.20 (0.10–0.40) |
| Bilirubin (mg/dL) | 178 | 0.20 (0.12) | 0.20 (0.1–1.0) |
| ALT (units/L) | 178 | 19 (17) | 15 (0–172) |
| eGFR normalized (mL/min/m2) | 178 | 128.9 (36.5) | 127.9 (33.2–263.5) |
| Male | 98 | ||
| Race a | |||
| European/white | 135 | ||
| African | 18 | ||
| Asian | 9 |
a
Only available for the 162 patients with germline DNA for genotype testing.
SD; standard deviation; BSA; body surface area; SCr; serum creatinine; ALT; alanine aminotransferase; eGFR; estimated glomerular filtration rate