Table 2.
Marginal Effects of Amyloid PET Scan, Cognition, and Everyday Function on Risk Taking (n=1,551 dyads)
| Model 1: Scan recipient willingness to accept risk |
Model 2: Risk care partner believes scan recipient will accept |
Model 3: Risk taking Discordancea (n=1,551) |
|||||
|---|---|---|---|---|---|---|---|
| Part 1: Probability willing to accept >0 risk (n=1,551) |
Part 2: Amount of risk conditional on willing to accept >0 (n=996) |
Unconditional Marginal Effect (95% CI) |
Part 1: Probability willing to accept >0 risk (n=1,551) |
Part 2: Amount of risk conditional on willing to accept >0 (n=1,130 |
Unconditional Marginal Effect (95% CI) |
Marginal Effect (95% CI) |
|
| Conditional Marginal Effect (95% CI) |
Conditional Marginal Effect (95% CI) |
Conditional Marginal Effect (95% CI) |
Conditional Marginal Effect (95% CI) |
||||
| Amyloid PET scan positive (ref = negative) | 0.05*
(0.01, 0.10) |
4.97*
(0.37, 9.57) |
5.62**
(1.98, 9.25) |
0.12***
(0.07, 0.17) |
4.01 (−0.33, 8.34) |
7.62***
(4.07, 11.18) |
2.58 (−2.00, 7.17) |
| Scan recipient characteristics (reported by scan recipient) | |||||||
| TICS-M | 0.01**
(0.00, 0.01) |
−0.73***
(−1.12, −0.33) |
−0.19 (−0.51, 0.13) |
0.00 (0.00, 0.01) |
−0.05 (−0.41, 0.31) |
0.05 (−0.27, 0.36) |
0.21 (−0.18, 0.60) |
| Age, y | 0.00 (−0.01, 0.00) |
0.29 (−0.10, 0.69) |
−0.01 (−0.32, 0.31) |
||||
| Female | −0.10***
(−0.16, −0.05) |
4.89*
(0.17, 9.61) |
−1.52 (−5.30, 2.49) |
||||
| Marital status (ref = married/living with partner) | |||||||
| Separated/divorced | 0.16**
(0.04, 0.27) |
−14.37*
(−25.60, −3.14) |
−4.15 (−13.68, 5.39) |
||||
| Widowed | 0.10 (−0.01, 0.20) |
−3.14 (−13.37, 7.10) |
2.21 (−6.46, 10.87) |
||||
| Never married | 0.09 (−0.12, 0.30) |
−9.78 (−29.89, 10.33) |
−2.93 (−19.29, 13.43) |
||||
| Education (ref = high school graduate or less) | |||||||
| Some college | 0.10*
(0.02, 0.17) |
−0.58 (−7.66, 6.50) |
4.22 (−1.44, 9.88) |
||||
| Bachelor's degree | 0.08*
(0.00, 0.16) |
−3.86 (−11.09, 3.37) |
1.49 (−4.22, 7.21) |
||||
| Advanced degree | 0.07 (0.00, 0.15) |
−7.41*
(−14.31, −0.50) |
−1.36 (−6.74, 4.01) |
||||
| Race (ref = White) | |||||||
| African American | 0.08 (−0.10, 0.25) |
−4.90 (−20.05, 10.24) |
0.06 (−12,89, 13.01) |
||||
| Other | 0.07 (−0.09, 0.23) |
3.29 (−10.26, 16.83) |
5.39 (−6.82, 17.60) |
||||
| Care partner characteristics (reported by care partner) | |||||||
| ECog-12 reported for person with cognitive impairment | 0.03 (−0.01, 0.06) |
0.71 (−2.57, 3.98) |
1.64 (−1.03, 4.32) |
0.06***
(0.02, 0.09) |
3.99*
(0.91, 7.07) |
5.20***
(2.56, 7.83) |
3.42*
(0.11, 6.72) |
| Age, y | −0.01*
(−0.01, 0.00) |
0.57***
(0.30, 0.85) |
0.28*
(0.04, 0.52) |
0.28 (−0.02, 0.58) |
|||
| Female | −0.02 (−0.07, 0.03) |
4.09 (−0.15, 8.32) |
2.24 (−1.38, 5.87) |
3.54 (−1.08, 8.16) |
|||
| Education (ref = high school graduate or less) | |||||||
| Some college | 0.04 (−0.03, 0.12) |
−2.77 (−9.11, 3.56) |
0.00 (−5.57, 5.57) |
−3.32 (−10.09, 3.46) |
|||
| Bachelor's degree | 0.01 (−0.06, 0.09) |
−7.74*
(−14.12, −1.36) |
−4.83 (−10.34, 0.68) |
−7.16*
(−13.96, −0.37) |
|||
| Advanced degree | 0.06 (−0.01, 0.13) |
−10.51*** (−16.77, −4.25) |
−5.23 (−10.67, 0.22) |
−3.32 (−10.04, 3.41) |
|||
| Race (ref = White) | |||||||
| African American | −0.03 (−0.21, 0.15) |
12.17 (−3.63, 27.98) |
7.28 (−7.12, 21.68) |
10.20 (−6.50, 26.91) |
|||
| Other | 0.02 (−0.13, 0.16) |
1.75 (−10.82, 14.31) |
1.96 (−9.19, 13.12) |
3.18 (−10.69, 17.05) |
|||
| Relationship to scan recipient (ref = spouse) | |||||||
| Child | −0.09 (−0.22, 0.03) |
2.11 (−7.41, 11.63) |
−2.53 (−10.62, 5.57) |
−1.07 (−11.41, 9.27) |
|||
| Other | 0.08 (−0.07, 0.14) |
10.35 (−0.15, 20.84) |
11.51*
(1.28, 21.74) |
13.69*
(1.52, 25.85) |
|||
| Someone else is the one person most involved in helping make decisions about the scan recipient’s health care if they are no longer able (ref = care partner) | 0.03 (−0.07, 0.14) |
8.42 (−0.48, 17.33) |
|||||
| Yes, the scan recipient has discussed their preferences for who should make health care decision if they are no longer able to make it (ref = no) | 0.06 (−0.01, 0.13) |
9.30 (−0.24, 18.84) |
0.58 (−4.68, 5.84) |
11.28*
(0.71, 21.84) |
|||
CI: Confidence interval
a
risk-taking discordance = care partner risk – scan recipient risk
*
p<0.05;
**
p<0.01;
***
p<0.001