Table 2.
Participant Characteristics by GDS vs. Meyer Grouping
| GDS(Un)/Meyer(Un) (U/U; n=172) |
GDS(Imp)/Meyer(Un) (I/U; n=36) |
GDS(Imp)/Meyer(Imp) (I/I; n=33) |
p | Pair-wise comparisons1 |
|
|---|---|---|---|---|---|
| Median [IQR], Mean (SD), or n (%) | |||||
| Demographics | |||||
| Age (years) | 43.4 (7.8) | 44.4 (6.1) | 44.6 (7.4) | 0.17 | |
| Gender (male) | 141 (82.0%) | 28 (77.8%) | 25 (75.8%) | 0.64 | |
| Ethnicity | -- | -- | -- | 0.09 | |
| Non-Hispanic White | 69 (40.1%) | 16 (44.4%) | 16 (48.5%) | -- | |
| African American | 85 (49.4%) | 15 (41.7%) | 9 (27.3%) | -- | |
| Hispanic | 15 (8.7%) | 5 (13.9%) | 8 (24.2%) | -- | |
| Other | 3 (1.7%) | 0 (0.0%) | 0 (0.0%) | -- | |
| Education (years) | 12.8 (2.4) | 13.3 (2.5) | 14.2 (2.3) | <0.01 | I/I > U/U |
| WRAT | 96.6 (13.0) | 91.7 (16.4) | 93.2 (14.0) | 0.09 | |
| Hollingshead2 | 40.5 (10.7) | 39.9 (12.2) | 38.4 (13.4) | 0.60 | |
| Employed | 56 (32.6%) | 11 (30.6%) | 13 (39.3%) | 0.70 | |
| HIV Disease Characteristics | |||||
| History of AIDS | 115 (66.9%) | 25 (69.4%) | 24 (72.7%) | 0.79 | |
| Detectable viral load3 | 86 (50.3%) | 17 (47.2%) | 13 (40.6%) | 0.60 | |
| Current CD4 count | 450 [267 – 621] | 477 [359 – 630] | 516 [268 – 667] | 0.35 | |
| Nadir CD4 count | 150 [36 – 300] | 155 [14 – 277] | 109 [28 – 224] | 0.36 | |
| Estimated duration of infection (years) | 11.2 [5.7 – 15.6] | 14.3 [5.0 – 17.9] | 12.7 [6.2 – 15.3] | 0.40 | |
| On ART | 127 (73.8%) | 30 (83.3%) | 31 (93.9%) | 0.03 | I/I > U/U |
| Failing ART (% detectable on ART) | 45 (35.4%) | 11 (36.7%) | 11 (36.7%) | 0.99 | |
| Medical Comorbidities and Characteristics | |||||
| Hypertension4 | 24 (14.6%) | 9 (25.7%) | 9 (28.1%) | 0.09 | |
| Hyperlipidemia4 | 16 (9.8%) | 5 (14.3%) | 5 (15.6%) | 0.52 | |
| Hepatitis C4 | 50 (30.5%) | 9 (25.7%) | 9 (28.1%) | 0.84 | |
| Diabetes4 | 18 (11.0%) | 5 (14.3%) | 4 (12.5%) | 0.85 | |
| Psychiatric Diagnoses | |||||
| LT MDD | 95 (55.2%) | 22 (61.1%) | 19 (57.6%) | 0.80 | |
| Current MDD5 | 15 (8.7%) | 7 (20.0%) | 1 (3.0%) | 0.05 | |
| LT SUD | 131 (76.2%) | 26 (72.2%) | 19 (57.6%) | 0.09 | |
| LT alcohol | 98 (57.0%) | 17 (47.2%) | 14 (42.4%) | 0.22 | |
| LT cannabis | 51 (29.7%) | 8 (22.2%) | 7(21.2%) | 0.46 | |
| LT methamphetamine | 30 (17.4%) | 6 (16.7%) | 5 (15.2%) | 0.95 | |
| Contributing Diagnoses | 43 (25.0%) | 12(33.3%) | 18 (54.6%) | <0.01 | I/I > U/U |
Note. GDS(Un)/Meyer(Un)=Unimpaired by both Meyer and GDS criteria; GDS(Imp)/Meyer(Un)= Impaired by GDS criteria and Unimpaired by Meyer; GDS(Imp)/Meyer(Imp)=impaired by both criteria. WRAT=Wide Range Achievement Test, 3rd edition; ART = antiretroviral therapy; BMI= body mass index; LT = lifetime; MDD = major depressive disorder; SUD = substance use disorder;
1
Pair-wise comparisons were examined using Tukey’s H.S.D. (α = 0.05) for continuous outcomes and Bonferroni-adjustments (α = 0.05/3 = 0.0167) for dichotomous outcomes
2
n=236;
3
n=239;
4
n=231;
5
n=240