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. 2020 Jan 23;8:48–55. doi: 10.1016/j.ibror.2020.01.001

Fig. 4.

Fig. 4

Expression of total JNK isoforms in chronic epilepsy. A. Western blot showing total expression of JNK1 isoform (phosphorylated plus non-phosphorylated) in chronic epilepsy and naïve control conditions. JNK1 expression was not significantly changed in the epileptic condition. B. Expression of JNK2 was reduced in epilepsy for both the 54 and 46 kDa variants. C. Expression of only the 54 kDa variant of JNK3 was significantly reduced under epileptic conditions. D. Quantification of JNK isoform expression in the epileptic condition as a percentage of control expression shows significant downregulation of both JNK2 variants as well as the 54 kDa JNK3 variant.