. 2019 Dec 16;29(3):506–514. doi: 10.1093/hmg/ddz272

Table 2.

GWAS and conditional single SNP association results in top regions

Conditional on	Chr:Pos (bp)	Gene (functional class)	SNP	Ref/Alt	Africans (AADM)						African Americans (ARIC + HUFS)						Meta-analysis
Conditional on	Chr:Pos (bp)	Gene (functional class)	SNP	Ref/Alt	N	AAF	Beta	SE	P value	r ²	N	AAF	Beta	SE	P value	r ²	AAF	Beta	SE	P value	r ²
NO	4:10000947	SLC2A9 (intron)	rs7683856	A/G	4126	0.784	0.216	0.027	6.94E−16	0.016	5007	0.775	0.281	0.024	1.62E−30	0.028	0.779	0.251	0.018	1.60E−44	0.022
	11:64367854	SLC22A12 (nonsynonymous)	rs147647315	G/A	4126	0.019	−0.579	0.082	1.82E−12	0.012	5007	0.012	−0.688	0.091	5.14E−14	0.011	0.015	−0.628	0.061	6.65E−25	0.012
rs7683856	11:64367854	SLC22A12 (nonsynonymous)	rs147647315	G/A	4126	0.019	−0.597	0.083	6.66E−13	0.013	5007	0.012	−0.711	0.090	2.53E−15	0.012	0.015	−0.649	0.061	1.24E−26	0.013
	4:9927620	SLC2A9 (intron)	rs6838021	T/C	4126	0.449	0.113	0.024	1.90E−06	0.006	5007	0.505	0.153	0.022	3.12E−12	0.012	0.480	0.135	0.016	5.75E−17	0.009
rs7683856, rs6838021	11:64367854	SLC22A12 (nonsynonymous)	rs147647315	G/A	4126	0.019	−0.587	0.083	1.33E−12	0.013	5007	0.012	−0.709	0.089	2.07E−15	0.012	0.015	−0.644	0.061	2.17E−26	0.012
rs7683856, rs6838021, rs147647315	11:64369267	SLC22A12 (insertion)	rs150284736	−/CCCTG	4126	0.216	0.070	0.026	0.008	0.002	5007	0.206	0.123	0.025	7.32E−07	0.005	0.211	0.098	0.018	5.37E−08	0.003