Extended Data Fig. 5. Amino acid, cofactor and nucleotide biosynthesis capacities of MK-D1 and other Asgard archaea.

Genomes that encode proteins for the synthesis of amino acids, cofactors and nucleotides from pyruvate or acetyl-CoA (dark blue) and synthesis from other intermediates (light blue) are indicated. Those without complete pathways from pyruvate and/or acetyl-CoA are indicated in white. Halodesulfovibrio sp. strain MK-HDV and Methanogenium sp. strain MK-MG isolated in this study are also shown.