Table 2.
Maternal dietary selenium intake and maternal blood selenium concentration according to maternal characteristics†
(Numbers of subjects and percentages; medians and interquartile ranges (IQR))
| Se intake from food (µg/d) | Blood Se concentration (µg/l) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| n | % | Median | IQR | P * | n | % | Median | IQR | P * | ||
| Total | 72 025 | 100 | 53 | 44–62 | 2638 | ||||||
| Maternal age (years) | <25 | 8284 | 12 | 50 | 41–62 | <0·0001 | 220 | 8 | 98 | 86–112 | <0·0001 |
| 25–29 | 24 411 | 34 | 52 | 43–62 | 947 | 36 | 102 | 88–116 | |||
| 30–34 | 30 524 | 42 | 53 | 45–63 | 1180 | 45 | 102 | 90–118 | |||
| >34 | 8806 | 12 | 54 | 46–64 | 291 | 11 | 105 | 91–122 | |||
| Pre-pregnancy BMI (kg/m2) | <18·5 | 2143 | 53 | 44–64 | <0·0001 | 81 | 3 | 104 | 91–116 | 0·024 | |
| 18·5–24·9 | 46 163 | 64 | 53 | 45–63 | 1703 | 65 | 102 | 90–119 | |||
| 25–30 | 15 189 | 21 | 52 | 43–62 | 611 | 23 | 101 | 88–116 | |||
| >30 | 6657 | 9 | 51 | 42–61 | 194 | 7 | 100 | 86–114 | |||
| Missing | 1873 | 3 | 53 | 44–62 | 49 | 2 | 101 | 93–113 | |||
| Parity | 0 | 38 310 | 53 | 52 | 43–62 | <0·0001 | 1515 | 57 | 104 | 91–119 | <0·0001 |
| 1 | 21 650 | 30 | 53 | 44–62 | 755 | 29 | 101 | 88–115 | |||
| 2 | 9700 | 13 | 54 | 45–63 | 317 | 12 | 100 | 87–115 | |||
| 3+ | 2306 | 3 | 54 | 45–64 | 50 | 2 | 91 | 81–103 | |||
| Missing | 59 | 0 | 56 | 45–64 | 1 | 0 | 112 | 112–112 | |||
| Preterm birth | Yes | 3618 | 5 | 52 | 44–62 | 0·022 | 80 | 3 | 103 | 90–114 | 0·769 |
| No | 68 407 | 95 | 53 | 44–62 | 2558 | 97 | 102 | 89–117 | |||
| Gestational age groups | Early preterm (GW 22–33) | 952 | 1 | 51 | 43–61 | 0·026 | 8 | 0 | 92 | 81–102 | 0·434 |
| Late preterm (GW 34–36) | 2666 | 4 | 53 | 44–62 | 72 | 3 | 104 | 93–115 | |||
| Early term (GW 37–38) | 11 660 | 16 | 53 | 44–63 | 410 | 16 | 102 | 89–117 | |||
| Late term (GW 39–42) | 56 747 | 79 | 53 | 44–62 | 2148 | 81 | 102 | 89–117 | |||
| Maternal education (years) | <13 | 22 424 | 31 | 51 | 42–62 | <0·0001 | 677 | 26 | 100 | 86–114 | <0·0001 |
| 13–16 | 29 854 | 41 | 53 | 44–62 | 1248 | 47 | 101 | 88–116 | |||
| >16 | 18 202 | 25 | 54 | 46–64 | 655 | 29 | 107 | 94–122 | |||
| Missing | 1545 | 2 | 51 | 42–62 | 58 | 2 | 98 | 87–115 | |||
| Smoking habits | Never | 65 765 | 91 | 53 | 44–62 | <0·0001 | 2462 | 93 | 102 | 90–118 | 0·001 |
| Occasionally | 1953 | 3 | 52 | 43–63 | 63 | 2 | 99 | 90–113 | |||
| Daily | 3900 | 5 | 52 | 42–62 | 103 | 4 | 95 | 85–110 | |||
| Missing | 407 | 1 | 52 | 43–62 | 10 | 0 | 97 | 90–114 | |||
| Alcohol consumption | No | 64 079 | 89 | 53 | 44–62 | <0·0001 | 2329 | 88 | 102 | 89–117 | 0·02 |
| Yes | 7946 | 11 | 54 | 46–63 | 309 | 12 | 104 | 92–120 | |||
| Iodine intake (µg/d) | <82 | 14 389 | 20 | 42 | 35–49 | <0·0001 | 510 | 19 | 101 | 88–118 | 0·50 |
| 82–108 | 14 389 | 20 | 49 | 42–56 | 554 | 21 | 103 | 90–118 | |||
| 108–135 | 14 389 | 20 | 52 | 45–60 | 523 | 20 | 102 | 89–117 | |||
| 135–174 | 14 389 | 20 | 57 | 50–65 | 554 | 21 | 103 | 91–117 | |||
| >174 | 14 389 | 20 | 65 | 56–75 | 497 | 19 | 101 | 88–116 | |||
| n-3 intake (g/d) | <0·25 | 26 547 | 37 | 46 | 38–54 | <0·0001 | 986 | 37 | 98 | 87–113 | <0·0001 |
| 0·25–0·47 | 24 548 | 34 | 53 | 46–61 | 977 | 37 | 105 | 91–118 | |||
| >0·47 | 20 851 | 29 | 62 | 53–72 | 675 | 26 | 106 | 92–120 | |||
| Protein intake (g/d) | <76 | 24 008 | 33 | 42 | 36–48 | <0·0001 | 868 | 33 | 102 | 88–118 | 0·79 |
| 76–93 | 24 009 | 33 | 53 | 47–59 | 907 | 34 | 102 | 89–117 | |||
| >93 | 24 008 | 33 | 65 | 58–74 | 863 | 32 | 102 | 90–117 | |||
| Fibre intake (g/d) | <26 | 24 008 | 33 | 43 | 37–51 | <0·0001 | 870 | 33 | 101 | 88–116 | 0·04 |
| 26–35 | 24 009 | 33 | 53 | 46–60 | 933 | 35 | 102 | 89–117 | |||
| >35 | 24 008 | 33 | 63 | 55–72 | 835 | 32 | 104 | 90–118 | |||
| Energy intake (MJ/d) | <8390 | 24 008 | 33 | 44 | 37–50 | <0·0001 | 913 | 35 | 103 | 90–118 | 0·21 |
| 8390–10 460 | 24 009 | 33 | 53 | 46–60 | 893 | 34 | 102 | 89–117 | |||
| >10 460 | 24 008 | 33 | 63 | 55–73 | 832 | 32 | 101 | 89–117 | |||
GW, gestational week.
P value obtained with the Mann–Whitney U test for two groups and the Kruskal–Wallis test for more than two groups.
Amount of daily Se intake from food (FFQ data) and concentration of Se in blood in mid-pregnancy, according to maternal characteristics, from 72 025 participants in the Norwegian Mother and Child Cohort Study. Se intake from food was assessed with an FFQ in gestational week 22. Blood Se concentration was measured in whole blood collected in GW 17–18 in a subsample of 2638 of the 72 025 participating mothers.