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. 2020 Feb 12;10:2480. doi: 10.1038/s41598-020-57736-x

Table 3.

Property showing signs of adaptive changes in Schistosoma spindale cox1.

Property Categories (Z-scores)
6 7 8
Equilibrium constant (ionization of COOH) 1.792*
Isoelectric point 4.248***
Short and medium range non-bonded energy 3.995***
Solvent accessible reduction ratio 2.168*
Power to be at the C-terminal −1.78*
Partial specific volume 4.543***
Helical contact area 4.385***

TreeSAAP results for cox1 analysis of the two S. spindale samples reveal that isoelectric point and short and medium range non-bonded energy show the most prominent signs adaptation. Only changes with P < 0.001 (***) are regarded as highly significant and useful in terms of adaptation. These adaptive changes in isoelectric point have been previously linked which adaptive changes to abiotic pressures.