Figure 10.

Combining gene expression data with bacterial OTUs discriminates the type of IBD and inflammatory state. sPLS-DA analysis was performed on a curated concatenated list of gene expression data and bacterial OTU abundance and grouped by class (CDI, CD inflamed; CDNI, CD noninflamed; UCI, UC inflamed; UCNI, UC noninflamed). (A) Graph of sPLS-DA visualized on components (comp) 1 and 3. (B) Receiver operating characteristics (ROC) curves were generated based on the sPLS-DA model using the area under the ROC curve function. Area under the curve calculations are shown. mRNA, messenger RNA.