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. 2020 Feb 7;21:100738. doi: 10.1016/j.bbrep.2020.100738

Table 1.

Deletion of Reg3b exacerbates lethality of CFLARs Tg mice.

Line B12
Reg3b
Total
Genotypes +/+ +/− −/−
XY No. 17 20 10 47
% 36.2 42.6 21.3 100
XCFY No. 0 1 0 1
% 0 100 0 100
XX No. 20 24 7 51
% 39.2 47.1 13.7 100
XCFX No. 9 10 3 22
%
40.9
45.5
13.6
100
Line B52 Reg3b Total
Genotypes
+/+
+/−
−/−
XY No. 23 39 14 76
% 30.3 51.3 18.4 100
XCFY No. 0 0 0 0
% 0 0 0 0
XX No. 30 44 17 91
% 33.0 48.4 18.7 100
XCFX No. 17 14 4 35
% 48.6 40.0 11.4 100

Female CFLARs Tg mice were crossed with two lines (B12 and B52) of Reg3b−/− mice and genotypes of the progeny were determined by PCR at 3–4 weeks after birth.