Table 1.
Deletion of Reg3b exacerbates lethality of CFLARs Tg mice.
| Line B12 |
Reg3b |
Total | |||
|---|---|---|---|---|---|
| Genotypes | +/+ | +/− | −/− | ||
| XY | No. | 17 | 20 | 10 | 47 |
| % | 36.2 | 42.6 | 21.3 | 100 | |
| XCFY | No. | 0 | 1 | 0 | 1 |
| % | 0 | 100 | 0 | 100 | |
| XX | No. | 20 | 24 | 7 | 51 |
| % | 39.2 | 47.1 | 13.7 | 100 | |
| XCFX | No. | 9 | 10 | 3 | 22 |
|
% |
40.9 |
45.5 |
13.6 |
100 |
|
| Line B52 | Reg3b | Total | |||
| Genotypes |
+/+ |
+/− |
−/− |
||
| XY | No. | 23 | 39 | 14 | 76 |
| % | 30.3 | 51.3 | 18.4 | 100 | |
| XCFY | No. | 0 | 0 | 0 | 0 |
| % | 0 | 0 | 0 | 0 | |
| XX | No. | 30 | 44 | 17 | 91 |
| % | 33.0 | 48.4 | 18.7 | 100 | |
| XCFX | No. | 17 | 14 | 4 | 35 |
| % | 48.6 | 40.0 | 11.4 | 100 | |
Female CFLARs Tg mice were crossed with two lines (B12 and B52) of Reg3b−/− mice and genotypes of the progeny were determined by PCR at 3–4 weeks after birth.