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. 2020 Feb 6;10:79. doi: 10.3389/fonc.2020.00079

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Copyright © 2020 Dong, Li, Lin, Lu, Liu, Lu, Tang, Li, Zhu, Liu, Qiu, Tian and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The relationships among miR-150-3p, LincRNA00494 and SRCIN1. (A) Both LincRNA00494 and SRCIN1 are targeted by miR-150-3p. miR-150-3p significantly decreased the luciferase signals of both LincRNA00494 and SRCIN1. (B) The SRCIN1 and LincRNA00494 levels were significantly decreased. Data are shown as the mean ± SEM (normalized to GAPDH). (C) The negative correlations between the LincRNA00494 expression levels and the SRCIN1 mRNA levels were tested. (D) The reporter vector was cotransfected into the NSCLC cells with LincRNA00494 siRNA or control siRNA. The luciferase signal was substantially decreased.