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. 2020 Jan 10;19:1134–1144. doi: 10.1016/j.omtn.2019.12.025

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Silenced circFNDC3B Expression Inhibits PTC Cell Migration, and Invasion and Promotes Cell Apoptosis

(A) The flow cytometry analysis showed that circFNDC3B knockdown increased the proportion of apoptotic TPC-1 cells. (B) The flow cytometry analysis showed that overexpression of circFNDC3B decreased the proportion of apoptotic K1 cells. (C) Cell migration and invasion assays showed that circFNDC3B knockdown substantially attenuated the migration and invasion of TPC-1 cells. (D) Cell migration and invasion assays showed that overexpression of circFNDC3B promoted the ability of cell migration and invasion of K1 cells. Data are listed as mean ± SD of at least three independent experiments. **p < 0.01.