Skip to main content
. 2020 Jan 14;19:1145–1152. doi: 10.1016/j.omtn.2019.12.034

Table 1.

Association/Dissociation Rate Constants and Binding Affinities of Apt01 and Apt02, which Were Analyzed by SPR

Aptamer Name Target kon/M−1s−1 koff/s−1 KD (nM)
Apt01 VEGFR-1 4.73 × 106 1.57 × 10−2 3.3
Apt01 VEGFR-2 3.73 × 104 3.86 × 10−3 100
Apt02 VEGFR-1 9.54 × 105 1.39 × 10−3 1.5
Apt02 VEGFR-2 1.32 × 105 4.16 × 10−3 32

SPR sensorgrams are shown in Figure S2.