Figure 2.

circRASSF2 Promotes Cell Proliferation and Migration of PTC Cells In Vitro

(A) CCK-8 assay showed that circRASSF2 knockdown significantly repressed cell proliferation of TPC-1 cells. (B) CCK-8 assay showing overexpression of circRASSF2 promoted the proliferation of K1 cells. (C) Colony-formation assay showed that circRASSF2 knockdown significantly reduced cancer cell colony-forming ability of TPC-1 cells. (D) Colony formation assay showed that overexpression of circRASSF2 significantly promoted cancer cell colony-forming ability of K1 cells. (E) Transwell assay showed that circRASSF2 knockdown inhibited the migratory and invasive capabilities of TPC-1 cells. (F) Transwell assay showed that overexpression of circRASSF2 significantly promoted the migratory and invasive capabilities of K1 cells. All tests were performed at least three times. Data were expressed as mean ± SD. ***p < 0.001;**p < 0.01.