Validation result summary
Test Parameter	Acceptance Criteria		Result
Accuracy	Recovery 90–110% ([18F]FET spiked with [18F]fluoride)		[18F]fluoride concentration	Recovery
			1%	105.0%
			3%	104.6%
			5%	105.9%
Repeatability	6 repetitions (5% [18F]fluoride)	RSD ≤5%	RSD = 1.96%
Intermediate Precision	RSD ≤5% (3 analysts)		RSD = 2.90%
Specificity	Resolution of > 2 between peaks		Resolution of[18F]fluoride and [18F]FET	Rs = 5.7
Limit of Quantification	S/N ratio ≥ 10		24 kBq/ml
Linearity	12–1232 kBq/ml (5 concentrations in triplicate)	R > 0.99	R = 0.995
Range	Reported value		4.8–1232 MBq/ml