Table 3.

Association of HbA1c categories with mortality.

	HbA1c group	HbA1c	n/N	Crude HR (95%-CI)	p-value	Adjusted HR (95%-CI)	p-value
All patients	normal range	<5.7%	90/452	1 (reference)		1 (reference)
	pre-diabetes range	5.7 to <6.5%	55/300	0.94 (0.67 to 1.32)	0.741	1.17 (0.82 to 1.69)	0.388
	diabetes range	≥6.5%	41/136	1.57 (1.09 to 2.25)	0.015	1.83 (1.21 to 2.75)	0.004
Patients with history of diabetes	normal range	<5.7%	8/26	2.24 (0.74 to 6.82)	0.154	1.44 (0.45 to 4.60)	0.537
	pre-diabetes range	5.7 to <6.5%	6/34	1 (reference)		1 (reference)
	diabetes range	≥6.5%	25/79	2.04 (0.81 to 5.14)	0.130	1.39 (0.53 to 3.65)	0.498
Patients without history of diabetes	normal range	<5.7%	82/426	1 (reference)		1 (reference)
	pre-diabetes range	5.7 to <6.5%	49/266	1.00 (0.70 to 1.43)	0.991	1.20 (0.81 to 1.76)	0.366
	diabetes range	≥6.5%	16/57	1.51 (0.88 to 2.58)	0.135	2.12 (1.16 to 3.90)	0.015

Mortality was adjusted for age, gender, active cancer, immobilization, heart failure, chronic lung disease, overt pulmonary embolism, history of major bleeding, high pulse, low blood pressure, anemia, high creatinine, body mass index and periods of anticoagulation as a time-varying covariate. HR = hazard ratio, n = number of events, N = number of patients.