Table 2.
Summary of Baseline Physiology and Laboratory Values
| Characteristic | Septic AKI (n = 96) | Septic Non-AKI (n = 96) | p Value |
|---|---|---|---|
| Age (years) (mean [SD]) | 59.53 (15.66) | 53.39 (16.55) | 0.009 |
| Male sex (%) | 57.30 | 47.90 | 0.193 |
| Temperature (°C) (median [IQR]) | 36.9 (36.5–37.7) | 37.45 (36.6–38.3) | 0.013 |
| Respiratory rate (times/min) (mean [SD]) | 23.91 (6.047) | 23.01 (5.224) | 0.273 |
| Heart rate (beats/min) (mean [SD]) | 101.95 (23.553) | 99.91 (19.851) | 0.517 |
| MAP (mmHg) (mean [SD]) | 86.65 (23.22) | 84.85 (15.69) | 0.53 |
| PaO2 (mmHg) (mean [SD]) | 89.42 (26.08) | 88.47 (32.69) | 0.824 |
| White cell count (109/mL) (mean [SD]) | 15.59 (10.46) | 13.98 (7.70) | 0.227 |
| Platelets (109/mL) (mean [SD]) | 132.04 (95.03) | 178.95 (129.327) | 0.005 |
| C-reactive protein (mg/L) (mean [SD]) | 95.07 (104.05) | 101.77 (90.08) | 0.653 |
| Procalcitonin (ng/mL) (mean [SD]) | 27.39 (37.74) | 8.48 (17.52) | <0.001 |
| Lactate (mM) (median [IQR]) | 1.5 (1.1–3.4) | 1.2 (0.6–2.5) | 0.009 |
| Blood urea nitrogen (mM) (mean [SD]) | 21.99 (9.58) | 9.96 (30.17) | <0.001 |
| Serum creatinine (μΜ) (mean [SD]) | 343.23 (224.12) | 71.00 (24.60) | <0.001 |
| Activated partial thromboplastin time (s) (mean [SD]) | 51.08 (22.10) | 43.42 (10.49) | 0.058 |
| Alanine aminotransferase (U/L) (mean [SD]) | 213.53 (503.67) | 89.14 (120.7) | 0.02 |
| Total bilirubin (μΜ) (mean [SD]) | 39.83 (64.66) | 24.23 (30.25) | 0.034 |
| Blood glucose (mM) (mean [SD]) | 8.73 (4.62) | 8.76 (6.35) | 0.962 |
| SOFA score (mean [SD]) | 7.8 (3.54) | 4.75 (2.33) | <0.001 |