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. 2020 Feb 6;13:16. doi: 10.3389/fnmol.2020.00016

FIGURE 6.

FIGURE 6

Blockade of MAPK pathway prevents LPA-induced neuronal damage, and alleviates mitochondrial dysfunction. The viability of neuronal PC12 cells was measured using CCK-8 kit (A). The apoptosis of neuronal PC12 cells was detected by TUNEL staining (B). The MMP of neuronal PC12 cells was estimated by Rh123 staining (C). Scale bar: 20 μm. Data are mean ± SEM of five independent experiments. ∗∗P < 0.01.