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. 2019 Sep 17;10(2):313–326. doi: 10.1016/j.apsb.2019.09.003

Figure 5.

Figure 5

GHMT-treated fibroblasts have fewer heterochromatin foci. (A) Immunofluorescence labeling of H3K4me3 on day 6 of reprogramming. Insets show a single cell nucleus at higher magnification. (B) The graph shows the number of heterochromatin foci per nuclei. (C) Immunofluorescence labeling of H3K4me3 by co-staining with NKX2-5. (D) ChIP analysis of β-catenin on promoter regions of MESP1 on day 6 of reprogramming. (E) ChIP analysis of H3K4me3 on promoter regions of cardiogenic and fibroblast genes on day 21 of reprogramming. Error bars indicate SEM. ∗P < 0.05. Scale bars, 10 μm.