Table 3.
The 41 suspected drugs involved in the 30 cases of TEN reported to the NPC between 2004 and 2017.
Drug name | Number of suspected drug per TEN case | Frequency of occurrence | Number of suspected drug involved in TEN n (%) |
---|---|---|---|
Camoquin, carbamazepine, and chlorpromazine | 3 | 1 | 3 (7.3) |
Cotrimoxazole, sulfadoxime-pyrimethamine, and nevirapine | 1 | 3 (7.3) | |
Subtotal | 2 | 6 (14.6) | |
Cotrimoxazole and nevirapine | 2 | 3 | 6 (14.6) |
Cotrimoxazole and efavirenz | 1 | 2 (4.9) | |
Carbamazepine and chlorpromazine | 1 | 2 (4.9) | |
Carbamazepine and artemether-lumefantrine | 1 | 2 (4.9) | |
Ceftazidime and levofloxacin | 1 | 2 (4.9) | |
Subtotal | 7 | 14 (34.2) | |
Sulfadoxime-pyrimethamine | 1 | 6 | 6 (14.6) |
Nevirapine | 4 | 4 (9.8) | |
Artemether-lumefantrine | 3 | 3 (7.3) | |
Cotrimoxazole | 2 | 2 (4.9) | |
Tetanus toxoid | 2 | 2 (4.9) | |
Chloroquine | 1 | 1 (2.4) | |
Ciprofloxacin | 1 | 1 (2.4) | |
Phenytoin | 1 | 1 (2.4) | |
Herbal product | 1 | 1 (2.4) | |
Subtotal | 21 | 21 (51.2) | |
TOTAL | 30 | 41 (100.0) |
NPC, National Pharmacovigilance Center; TEN, toxic epidermal necrolysis.