Figure 1.

Sample data from Lorrca® with Oxygenscan. (a) EImax indicates deformability under oxygenated conditions; EImin under deoxygenated conditions; PoS is the oxygen concentration at which deformability declines. (b) HbAA RBCs are unaffected by hypoxia while HbAS shows a slight reduction in deformability at low pO₂ and HbSS RBCs deformability declines precipitously with hypoxia. (c,d) Hydroxyurea and transfusion improve deformability of the RBC populations.²² (A color version of this figure is available in the online journal.)