Figure 6.
Docked conformation of the dapsone (a) and kaempferol (b) into the DHPS pABA pocket. The left panel displays 3D conformation of the inhibitors (dapsone in grey carbon and kaempferol in green carbon) and the right panel shows 2D representation of enzyme-inhibitor interactions. The dotted pink arrows indicate hydrogen bond interactions through amino acid side chains and the solid pink arrows represent hydrogen bond interactions through backbone atoms.