Table 1.
Potential therapeutic targets for Kaempferol identified by using shape-based screening method.
Rank | Drug Name | Structure | Hybrid Score | Shape Score | Feature Score | Target | Validation |
---|---|---|---|---|---|---|---|
1 | Dienestrol | Figure 23 | 1.381 | 0.8505 | 0.5307 | Estrogen receptor | Experimental |
2 | Dapsone | Figure 24 | 1.344 | 0.8834 | 0.460 | Dihydropteroate synthase | In silico |
3 | Sulfadiazine | Figure 25 | 1.296 | 0.8761 | 0.42 | Dihydropteroate synthase | In silico |
4 | Sulfacytine | Figure 26 | 1.289 | 0.8566 | 0.432 | Dihydropteroate synthase | In silico |
5 | Sulfamerazine | Figure 27 | 1.271 | 0.8679 | 0.403 | Dihydropteroate synthase | In silico |