Table 4.

Associations Between Stress and/or Anxiety and Uncinate Fasciculus Microstructural Properties

Regression	R2	Adj R2	F	Stressful Events						STAI-TR
				B	β	t	p	q	95% CI	B	β	t	p	q	95% CI
L-UF FA	.375	.354	18.113	−0.000005	−.018	−0.344	.731	.820	−.000034 to .000024	0.00017	.110	2.129	.034	.145	.000013 to .00033
R-UF FA	.414	.394	21.346	0.000016	.054	1.088	.278	.467	−.000013 to .000046	0.000073	.045	0.891	.374	.514	−.000089 to .00023
L-UF MD	.448	.429	24.509	0.00016	.149	3.095	.002	.012a	.000061 to .00027	−0.00039	−.064	−1.315	.190	.419	−.00097 to .00019
R-UF MD	.456	.438	25.362	0.00011	.093	1.944	.053	.199	−.000001 to .00022	−0.00062	−.098	−2.018	.045	.180	−.0012 to −.000015
L-UF AD	.377	.356	18.280	0.00019	.177	3.464	.001	.007a	.000082 to .00030	−0.00023	−.040	−0.781	.436	.545	−.0008 to .00035
R-UF AD	.391	.370	19.385	0.00015	.142	2.804	.005	.026a	.000047 to .00027	−0.00067	−.112	−2.18	.030	.137	−.0012 to −.000065
L-UF RD	.467	.449	26.473	0.00015	.133	2.812	.005	.026a	.000047 to .00026	−0.00046	−.073	−1.535	.126	.350	−.0010 to .00013
R-UF RD	.472	.455	27.063	0.000086	.069	1.469	.143	.366	−.000029 to .00020	−0.00060	−.089	−1.876	.062	.220	−.0012 to .00003

Results from multiple regression analyses showing the model fit, as well as associations between stress and/or anxiety and uncinate fasciculus microstructural properties. The other covariates in the regression model are gestational age at birth, postmenstrual age at scan, maternal age, sex, socioeconomic status, and days on parenteral nutrition (see the Supplement).

AD, axial diffusivity; Adj, adjusted; B, unstandardized beta coefficient; β, standardized beta coefficient; CI, confidence interval; FA, fractional anisotropy; L, left; MD, mean diffusivity; q, corrected p value using Benjamini-Hochberg false discovery rate correction; R, right; RD, radial diffusivity; STAI-TR, State Trait Anxiety Inventory–Trait Anxiety; UF, uncinate fasciculus.

^aSignificant results at p < .05.