Comparison 2. Prophylactic studies: CSF versus control.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 All cause mortality to 10 days after intervention complete	3	359	Risk Ratio (M‐H, Fixed, 95% CI)	0.59 [0.24, 1.44]
1.1 G‐CSF	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 GM‐CSF	3	359	Risk Ratio (M‐H, Fixed, 95% CI)	0.59 [0.24, 1.44]
2 Sepsis incidence to 10 days after intervention complete, in neutropenic / neutropenia high risk infants	1	31	Risk Ratio (M‐H, Fixed, 95% CI)	0.59 [0.25, 1.39]
3 Sepsis incidence to 10 days after intervention complete, stratified by sepsis identification criteria	3	359	Risk Ratio (M‐H, Fixed, 95% CI)	0.93 [0.71, 1.21]
3.1 Sepsis identified by clinical plus microbiological criteria	1	75	Risk Ratio (M‐H, Fixed, 95% CI)	0.66 [0.36, 1.20]
3.2 Sepis identified by either clinical or microbiological criteria	2	284	Risk Ratio (M‐H, Fixed, 95% CI)	1.02 [0.76, 1.37]