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High COX-2 expression in gastric tumors correlates with reduced disease-free and overall survival in AN gastric cancer patients. Representative COX-2 protein expression (A) low and (B) high in gastric cancer tissue. (C) 5-year disease-free survival rate of patients with COX-2 high (n = 13) or low (n = 72) expressing tumors, p = 0.01. (D) 5-year overall survival rate of patients with COX-2 high (n = 13) or low (n = 72) expressing tumors, p = 0.004. Scale bars; 100 μm.
