Table 1.
Statistical testing dependence of the DNA repair foci and γH2AX pan-staining on dose, post-irradiation time, and treatment with the DNaseI
| Variables | Multifactorial ANOVA | Categorical Factors | p-Values Adjusted by FDR | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| γH2AX * | 53BP1 * | γH2AX/53BP1 * | Pan-st. (%) | Multivariate | Univariate | Time | Dose | Treatment | Time | Dose | Treatment |
| + | + | + | - | + | - | all | + | + | 0.00000 | 0.00000 | 0.74331 |
| + | - | - | - | - | + | all | + | + | 0.00000 | 0.00000 | 0.65262 |
| - | + | - | - | - | + | all | + | + | 0.00000 | 0.00000 | 0.92818 |
| - | - | + | - | - | + | all | + | + | 0.00006 | 0.00000 | 0.96429 |
| - | - | - | + | - | + | all | + | + | 0.10375 | 0.93183 | 0.70285 |
| + | + | + | - | + | - | 30 min | + | + | - | 0.00000 | 0.90202 |
| + | - | - | - | - | + | 30 min | + | + | - | 0.00000 | 1.00000 |
| - | + | - | - | - | + | 30 min | + | + | - | 0.00000 | 1.00000 |
| - | - | + | - | - | + | 30 min | + | + | - | 0.00011 | 1.00000 |
| - | - | - | + | - | + | 30 min | + | + | - | 0.84416 | 1.00000 |
| + | + | + | - | + | - | 2 h | + | + | - | 0.00000 | 0.15215 |
| + | - | - | - | - | + | 2 h | + | + | - | 0.00000 | 0.19180 |
| - | + | - | - | - | + | 2 h | + | + | - | 0.00000 | 0.14320 |
| - | - | + | - | - | + | 2 h | + | + | - | 0.00006 | 0.83501 |
| - | - | - | + | - | + | 2 h | + | + | - | 0.91106 | 0.70876 |
| + | + | + | - | + | - | 22 h | + | + | - | 0.00000 | 1.00000 |
| + | - | - | - | - | + | 22 h | + | + | - | 0.00000 | 1.00000 |
| - | + | - | - | - | + | 22 h | + | + | - | 0.00000 | 1.00000 |
| - | - | + | - | - | + | 22 h | + | + | - | 0.00000 | 0.97244 |
| - | - | - | + | - | + | 22 h | + | + | - | 0.92655 | 0.64110 |
* mean, foci per cell; + the data were included in analysis; - the data were not included in analysis. Statistically significant values are marked red.