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Scheme of CD38- and CD157-mediated pathways related to social behavior. The scheme shows the possible molecular mechanisms for increases in brain oxytocin (OT). One is OT release due to CD38 and CD157. Another is owing to receptor for advanced glycation end-products (RAGE)-dependent transport of OT into the brain. CD38- and CD157-dependent social behaviors are listed. The increased OT may trigger prosocial behavior.
