Table 1.

MiRNAs involved in regulation of angiogenesis during wound healing.

MiRNA	Functions	Ref.
MiR-21	TGF-β–mediated wound contraction Exosomal miR-21 promotes angiogenesis through PTEN and SPRY1 suppression	[16,17]
MiR-26a	Impairs angiogenesis by targeting SMAD1	[18]
MiR-27b	Facilitates angiogenesis by downregulation of THBS1, Sema6A and p66Shc	[19]
MiR-92a	Angiogenesis in fracture healing could increase by miR-92a inhibition	[20]
MiR-125a	Enhances angiogenesis by DLL4 repression	[21]
MiR-126	Blood vessel formation through VEGF and bFGF signaling	[22]
MiR-135a-3p	Inhibits angiogenesis by targeting of VEGF-HIP1-p38K signaling	[23]
MiR-148b	Promotes wound healing by TGFβ signaling regulation	[24]
MiR-199a-5p	Suppresses angiogenesis by targeting of the Ets-1-MMP1 pathway	[25]
MiR-615-5p	Suppresses angiogenesis by regulation of the VEGF-AKT/eNOS signaling pathway	[26]