Figure 1.

A 43-year-old patient with FL involving mediastinal and retroperitoneal (paraaortic) lymph nodes (blue arrowheads), as well as possible involvement of axillary and iliac lymph nodes. At interim restaging after three cycles of R-BENDA, the [¹⁸F]FDG uptake had decreased to Deauville ≤3 (i.e., not exceeding the liver uptake) in all nodal regions, which fulfills the Lugano criterion for CR. However, since the sum of the longest diameters (SLD) had only decreased by 24%, this represents MiR according to RECIL (Response Evaluation Criteria in Lymphoma) at interim restaging. At end-of-treatment (EOT), the SLD had finally decreased to 50%, consistent with CR according to both RECIL and Lugano.