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. 2019 Dec 31;12(1):99. doi: 10.3390/cancers12010099

Figure 2.

Figure 2

(a) Interface between areas of classical clear-cell carcinoma (black arrow) and its sarcomatoid component (blue arrow), Hematoxylin Eosin staining. (b) A higher density of tumor-infiltrating mononuclear inflammatory cells expressing PD-L1 is observed in the sRCC area compared to the clear-cell RCC one (monoclonal mouse antibody clone 22C3, hematoxylin counter staining). In this case, there is no PD-L1 expression on tumor cells.