Table 1.

Grading of CNS tumors mentioned in this review according to WHO guidelines [1].

Tumor Type	Grade
Diffuse Astrocytic and Oligodendroglial Tumors
Diffuse astrocytoma (IDHmut)	II
Oligodendroglioma (IDHmut-1p/19q deleted)	II
Anaplastic astrocytoma (IDHmut)	III
Anaplastic Oligodendroglioma (IDHmut-1p/19q deleted)	III
Diffuse midline Glioma (H3K27Mmut)	IV
Glioblastoma (IDHwt)	IV
Glioblastoma (IDHmut)	IV
Ependymal Tumor
Subependymoma	I
Myxopapillary ependymoma	I
Ependymoma	II
Ependymoma (RELA fusion-positive)	II/III
Anaplastic Ependymoma	III
Embryonal Tumors
Medulloblastoma	IV
Embryonal tumors with multilayered rosette	IV
Medulloepithelioma	IV
CNS Embryonal tumors	IV
Atypical teratoid/rhabdoid tumor	IV
CNS Embryonal tumors with rhabdoid features	IV