Table 3.
cDNA Microarray analysis in the field of vestibular schwannoma research.
| Methods | No of Tumor Samples | No and Type of Control Samples | Author, Year |
|---|---|---|---|
| cDNA Microarray, RT-PCR | 31 CYS-VS 6 SPO-VS |
No | [45] |
| cDNA Microarray, Cell cultures, Western Blotting | 36 SPO-VS 13 NF2-VS |
7 vestibular nerves | [39] |
| cDNA Microarray, RT-PCR, MLPA analysis of NF2 LOH analysis | 28 SPO-VS 3 NF2-VS |
2 auricular nerves 2 cervical nerves 1 facial nerve 1 vestibular nerve 1 nerve from the VIII cranial pair 1 commercial normal human adult Schwann cell (HSC) RNA |
[48] |
| cDNA Microarray, RT-PCR, IHC | 15 SPO-VS 7 CYS-VS 3 RAD-VS |
3 tibial nerves | [33] |
| cDNA Microarray, RT-PCR, IHC | 13 VS | No | [46] |
| cDNA Microarray | 16 SPO-VS | 3 vestibular nerves | [34] |
| cDNA Microarray, RT-PCR | 11 SPO-VS | 11 blood samples | [47] |
| cDNA Microarray, RT-PCR, IHC | 3 SPO-VS 1 CYS-VS 3 RAD-VS |
1 vestibular nerve | [26] |
| cDNA Microarray, IHC | 36 SPO-VS 13 NF2-VS 9 CYS-VS 9 RAD-VS |
7 vestibular nerves | Current study |
cDNA: complementary DNA; CYS-VS: cystic vestibular schwannoma; IHC: immunohistochemistry; LOH: loss of heterozygosity; MLPA: multiplex ligation-dependent probe amplification; NF2-VS: neurofibromatosis type 2-associated vestibular schwannoma; RAD-VS: irradiated vestibular schwannoma; RT-PCR: real-time polymerase chain reaction; SPO-VS: sporadic vestibular schwannoma.