Skip to main content
. 2019 Dec 23;9(1):45. doi: 10.3390/cells9010045

Figure 1.

Figure 1

Confirmation of the induction of gene expression by methylmercury via HOXB13. Human embryonic kidney cells (HEK293) cells were transfected with control siRNA or HOXB13 siRNA for 48 h and exposed to indicated concentration of methylmercuric chloride (MeHgCl) for 6 h. Quantitative PCR (qPCR) for the top four genes listed in Table 1 ((A) HSP6A, (B) OSM, (C) RFPL4A, and (D) RASD1) was performed. Representative data indicate relative values, with control as 1, normalized to each glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA level. The values are presented as mean ± S.D. of three individual experiments. * p < 0.05 vs. control, ** p < 0.01 vs. control, † p < 0.05 vs. control siRNA, †† p < 0.01 vs. control siRNA.