Figure 8.

DSF/Cu inhibits the growth of 5-8F xenografts via targeting tumor cells. (A) Schematic outline for in vivo drug treatment. (B) Photographs of subcutaneously growing human 5-8F xenografts extracted from mice at day 13. (C) The growth curves of tumors in mice treated by the indicated drugs. Data are shown as means ± SD. *** p < 0.001, n = 5. (D) Time-course diagram of mice weight. Data are shown as means ± SD. ** p < 0.01, n = 5. (E) Representative hematoxylin and eosin (H&E) staining on tumor biopsies. Scale bar: 100 μM. (F) Immunochemical staining of ki67 in tumor tissue slices from the indicated formulation-treated groups. Scale bar: 50 μM.