Figure 2.

Published pathogenic protein changes of D4ST1 and DSE in mcEDS. (A) Previously published truncating and non-truncating protein alterations in D4ST1 are shown in upper and lower panels, respectively. Black box indicates 5′-phosphosulfate binding site and gray box indicates 3′-phosphate binding site. (B) Previously published truncating and non-truncating protein alterations in DSE are shown in upper and lower panels, respectively. Black box indicates the signal peptide.