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. 2019 Dec 18;9(1):11. doi: 10.3390/cells9010011

Figure 6.

Figure 6

Effect of IL-18Rα on the production of anti-collagen antibodies after collagen-induced arthritis (CIA). Serum samples were collected from the wild-type (WT) and IL-18Rα KO mice on days 0 (n = 4 and n = 4), 2 (n = 12 and n = 8), 4 (n = 10 and n = 15), and 14 (n = 8 and n = 6). Each sample was analyzed by an ELISA. The levels of total IgG, IgG1, IgG2a, and IgG2b-anti-collagen antibodies in the WT and IL-18Rα KO mice and from the mice not injected with type II collagen were measured. Values are mean ± SEM. * p < 0.05.