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. 2019 Dec 18;9(1):11. doi: 10.3390/cells9010011

Figure 8.

Figure 8

Effect of IL-18Rα on the suppressors of cytokine signaling (SOCS) expression after collagen-induced arthritis (CIA). The gene expressions (A) in wild-type (WT) and IL-18Rα KO mice on day 2 (n = 12 and 8), day 4 (n = 10 and 15), and day 14 (n = 8 and 6) after LPS injection were assayed by real-time PCR. Protein levels (B) were evaluated by Western blotting (WT and IL-18Rα KO, n = 5 each). A representative band of SOCS3 and β-actin is shown (C). The data are mean ± SEM. ** p < 0.01, *** p < 0.001, WT vs. IL-18Rα KO mice.