Table 2.

Organ distribution of free DOX, DOX-loaded CA NPs, DOX-loaded CMCA NPs, and DOX-loaded α-KAMCA NPs at 2 h of treatment (n = 5).

Organs	Free DOX (ng/mg)	DOX–CA (ng/mg)	DOX–CMCA (ng/mg)	DOX–α-KAMCA (ng/mg)
Liver	0.3 ± 0.01	0.92 ± 0.04	0.3 ± 0.01	0.82 ± 0.11
Spleen	0.13 ± 0.01	0.22 ± 0.01	0.13 ± 0.01	0.21 ± 0.02
Heart	2.86 ± 0.23	1.39 ± 0.12	1.16 ± 0.08	0.77 ± 0.02
Lungs	0.11 ± 0.01	0.12 ± 0.01	0.14 ± 0.01	0.14 ± 0.01
Brain	0.29 ± 0.02	0.94 ± 0.01	0.64 ± 0.06	0.55 ± 0.04
Kidney	1.45 ± 0.01	0.69 ± 0.05	1.27 ± 0.07	0.77 ± 0.08
Tumor	0.37 ± 0.01	1.64 ± 0.06	2 ± 0.01	2.75 ± 0.31