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. 2020 Jan 8;11(1):71. doi: 10.3390/genes11010071

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Schematic representation of the role of different helicases, dissolvases and resolvases in the repair of mitotic/meiotic DNA double-strand breaks (DSBs). The diagram represents some of the more relevant DNA structures generated in response to a DSB during the execution of homologous recombination (HR) and the final outcomes produced after repair. Black lettering represents overlapping roles for a specific complex in both the mitotic and meiotic processing of the DSB. Green lettering represents meiosis-specific features. SDSA: Synthesis-Dependent Strand Annealing, DSBR: Double Strand Break Repair.