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. 2012 Sep 12;2012(9):CD004418. doi: 10.1002/14651858.CD004418.pub4

Kohno 2011.

Methods Randomized, open‐label, non‐inferiority study
Multicenter
Participants Adults (mean age: 58.5) 
 CAP mild to severe (70% moderate)
Interventions Atypical: IV levofloxacin 500 mg X 1/d for 7 to 14 days 
 Non‐atypical: IV ceftriaxone 1 G X 2/d for 7 to 14 days
Outcomes Success: clinical, radiological and laboratory
Notes Study in Japanese
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Central, registration control system
Allocation concealment (selection bias) Low risk Evaluator center, randomly allocated patients
Incomplete outcome data (attrition bias) 
 Mortality High risk 200/260 patients evaluated
Incomplete outcome data (attrition bias) 
 Failure High risk 200/260 patients evaluated
Selective reporting (reporting bias) Low risk Not identified
Other bias Low risk Not identified
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Open label trial
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk A separate party committee evaluated the effects of the drugs, not knowing which drug had been used