| Methods |
Randomized
Multicenter |
| Participants |
Adults (mean age: 62)
Hospitalized
CAP |
| Interventions |
Atypical: PO temafloxacin 600 mg X 2/d
Non‐atypical: IV cefotaxime 2 G X 3/d |
| Outcomes |
Cure: all signs and symptoms resolved
Improvement: reduction of severity or numbers of signs and symptoms
Failure: evidence of fever or worsening of signs, symptoms or chest X‐ray after 3 treatment days
Modification = ? |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Not identified |
| Allocation concealment (selection bias) |
Unclear risk |
Not identified |
| Incomplete outcome data (attrition bias)
Mortality |
Low risk |
All patients evaluated |
| Incomplete outcome data (attrition bias)
Failure |
High risk |
75/100 patients evaluated |
| Selective reporting (reporting bias) |
Low risk |
Not identified |
| Other bias |
Unclear risk |
Sponsored |
| Blinding of participants and personnel (performance bias)
All outcomes |
High risk |
None |
| Blinding of outcome assessment (detection bias)
All outcomes |
High risk |
None |
