| Methods |
Randomized
Multicenter |
| Participants |
Adults (mean age: 42)
Hospitalized
CAP |
| Interventions |
Atypical: PO sparfloxacin 400 mg X 1/d followed by 200 mg X 1/d
Non‐atypical: PO amoxacillin 1 G X /d |
| Outcomes |
Success: resolution of signs and symptoms
Modification = failure |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Not described |
| Allocation concealment (selection bias) |
Unclear risk |
Not described |
| Incomplete outcome data (attrition bias)
Mortality |
Low risk |
All patients evaluated |
| Incomplete outcome data (attrition bias)
Failure |
High risk |
266/329 patients evaluated |
| Selective reporting (reporting bias) |
Low risk |
Not identified |
| Other bias |
Low risk |
|
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Double‐blind |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Double‐blind |
